{
  "_description": "ex vivo 2×2 시너지 실험 몬테카를로 검정력. estimand=Bliss 초과 δ, 델타법 SE, 단측α=0.05.",
  "assumptions": {
    "H_um_per_9d": 250.0,
    "aga_deficit": 0.5,
    "donor_sd": 0.15,
    "alpha": 0.05,
    "sided": 1,
    "caveat": "SE 를 알려진 것으로 근사(부트스트랩 대비 약간 낙관적). ARM 효능<E 시 시너지↓."
  },
  "scenarios": {
    "기준(E=0.6)": {
      "true_delta": 0.1224,
      "cv": 0.3,
      "grid": {
        "4d_10f": 0.227,
        "4d_15f": 0.342,
        "4d_20f": 0.432,
        "4d_30f": 0.58,
        "4d_40f": 0.684,
        "4d_60f": 0.856,
        "4d_80f": 0.942,
        "4d_120f": 0.991,
        "6d_10f": 0.335,
        "6d_15f": 0.473,
        "6d_20f": 0.581,
        "6d_30f": 0.752,
        "6d_40f": 0.861,
        "6d_60f": 0.956,
        "6d_80f": 0.994,
        "6d_120f": 1.0
      },
      "reco_80pct": {
        "donors": 4,
        "follicles_per_group": 60
      }
    },
    "낙관(E=0.6,저변동)": {
      "true_delta": 0.1224,
      "cv": 0.22,
      "grid": {
        "4d_10f": 0.366,
        "4d_15f": 0.518,
        "4d_20f": 0.625,
        "4d_30f": 0.811,
        "4d_40f": 0.899,
        "4d_60f": 0.983,
        "4d_80f": 0.995,
        "4d_120f": 1.0,
        "6d_10f": 0.515,
        "6d_15f": 0.672,
        "6d_20f": 0.816,
        "6d_30f": 0.928,
        "6d_40f": 0.972,
        "6d_60f": 0.998,
        "6d_80f": 1.0,
        "6d_120f": 1.0
      },
      "reco_80pct": {
        "donors": 4,
        "follicles_per_group": 30
      }
    },
    "보수(E=0.4)": {
      "true_delta": 0.0586,
      "cv": 0.35,
      "grid": {
        "4d_10f": 0.074,
        "4d_15f": 0.1,
        "4d_20f": 0.102,
        "4d_30f": 0.181,
        "4d_40f": 0.222,
        "4d_60f": 0.289,
        "4d_80f": 0.368,
        "4d_120f": 0.49,
        "6d_10f": 0.102,
        "6d_15f": 0.141,
        "6d_20f": 0.172,
        "6d_30f": 0.227,
        "6d_40f": 0.304,
        "6d_60f": 0.374,
        "6d_80f": 0.475,
        "6d_120f": 0.646
      },
      "reco_80pct": null
    }
  },
  "recommendation": {
    "기준(E=0.6)": [
      4,
      60
    ],
    "낙관(E=0.6,저변동)": [
      4,
      30
    ],
    "보수(E=0.4)": null
  }
}